Organized by the Faculty of Veterinary Medicine of Ankara University, the 2nd International and the 10th National Conference on “Veterinary Biochemistry and Clinical Biochemistry: Advances and Challenges in Understanding the Mechanism of Diseases” was held on 24-26 October 2019. The conference provided a scientific platform for the scientists from universities, research centers and industries from all over the world to come together and share experiences and information through plenaries, short lectures and presentations.

The Directorate of Press and Public Relations Office released that the Head of the Department of Biochemistry of the Faculty of Veterinary Medicine of Near East University, Assistant Professor Serkan Sayıner, and two research assistants Deniz Ceylanlı and Sevgi Gençosman participated in the 2nd International and the 10th National Conference on Veterinary Biochemistry and Clinical Biochemistry and made three presentations. Asst. Prof. Dr. Serkan Sayıner's oral presentation on "Effects of Deep-Frying Sunflower Oil Alone and in Combination with Probiotics in Mice: A Biochemical, Histological and Spermatological Approach" was deemed worthy for the first prize award.

According to the press release, the study had been carried out with the support of the Center of Excellence and within the scope of a project, in which Professor Nurhayat Gülmez, Head of the Department of Histology, Associate Professor Murat Gülmez and Assistant Professor Zafer Sabit took place.

Infertility is one of the most important problems of the era...
Serkan Sayıner's research study on "Effects of Deep-Frying Sunflower Oil Alone and in Combination with Probiotics in Mice: A Biochemical, Histological And Spermatological Approach" presents data that both raw and deep-frying sunflower oil not only has negative effects on blood fats and on male reproductive organs and sperm quality but also causes oxidative damage. During the experiments, probiotics have also been used in combination with deep-frying sunflower oil to investigate the protective effect of probiotics against negative effects caused by sunflower oil. During the experiments that based on gut-brain axis, which is one of the latest concepts of the era, probiotics have also been used to investigate the protective effect of probiotics against negative effects caused by the frying sunflower oil. Based on the results acquired from the experiments carried out within the scope of the study, it can be said that probiotics are beneficial to the health of their host and consumption of probiotics can restore a healthy gut microbiome and prevent or alleviate such negative effects. The study also presents data that fast-food dietary habits are closely associated with the risk of infertility. In this regard, the study constitutes a model to better understand the effects of fast-food dietary habits on global fertility rates.

The Effect of Deep-Frying Palm Oil Consumption on Sperm Quality and Protective Effect of Kefir have been investigated...
Deniz Ceylanlı, research assistant at the Department of Biochemistry of the Faculty of Veterinary Medicine of Near East University, presented her study on "The Consequences Of Deep frying Palm Oil Consumption on Blood Lipids, Lipid Peroxidation and Spermatological Parameters in Mice: Could Kefir Be Protective Against Possible Adverse Effects".

The study had been carried out with the support of the Center of Excellence and within the scope of a multidisciplinary project, in which Professor Nurhayat Gülmez, Head of the Department of Histology, Associate Professor Dilek Arsoy, Head of the Department of Zootechnics and Animal Nutrition, Assistant Professor Serkan Sayıner, Head of the Department of Biochemistry, Assistant Professor Ayfer Fındık, Head of the Department of Virology, and Associate Professor Murat Gülmez took place.

Grounding on the experimental results, Deniz Ceylanlı's study presents data that deep-frying palm oil has negative effects on male reproductive organ and impairs the sperm quality. Experimental findings also show that deep-frying palm oil leads not only an increase in the percentage of abnormal sperm but also a decrease in testicular tissue score.

Based on the findings acquired from investigations on the effects of kefir, the study presents data that the consumption of kefir reduces lipid peroxidation and may contribute to reduce the negative effects caused by the consumption of deep-frying palm oil.

High-dose Paracetamol induces organ toxicity...
Research assistant Sevgi Gençosman presented her study titled "The protective effect of Ambroxol in acetaminophen induced hepatotoxicity in rats" at the conference and attracted great attention.

Based on the experimental results, Sevgi Gençosman's study presents significant data that long term use of a single or high dose acetaminophen, which is also known as paracetamol and commonly used to treat pain and fever, causes oxidative stress that induces organ toxicity, especially liver toxicity. Considering the inflammatory, oxidative stress and apoptotic effects that induce organ toxicity by long-term use of a single dose or high-dose acetaminophen, the study has investigated the possible protective effect of ambroxol on hepatotoxicity and organ toxicity. The findings acquired through experiments conducted within the objective of the study show that ambroxol restores antioxidant enzyme activities and stores liver enzyme activities to normal levels. Since acetaminophen, also known as paracetamol, is used as a painkiller by a large population, the findings that long-term use of paracetamol causes organ damage, when used at higher doses, are important. The observational findings regarding the protective effects of ambroxol on organ damage induced by acetaminophen are also significant. Therefore, this study paves the way towards further investigations on the issue. Based on the observational findings, the study recommends the co-administration of ambroxol with acetaminophen to prevent long-term adverse effects, including organ damage potentially caused by the use of acetaminophen.

The study has been conducted with a multidisciplinary approach grounding on the scientific collaboration with Associate Professor Ahmet Özer Şehirli, lecturer at the Department of Basic Medical Sciences of the Faculty of Dentistry of Near East University, Assistant Professor Serkan Sayıner, Head of the Department of Biochemistry of NEU Faculty of Veterinary Medicine, research assistant Sevgi Gençosman and Hüseyin Şahin, research assistant at the Department of Histology.

The Studies conducted by Near East University Faculty Members attracts attention...
Throughout the three-day lasting conference, academicians, scientists and experts from universities and research centers from all over the world participated in plenaries, short lectures and sessions and delivered lectures or made oral or poster presentations on cancer, apoptosis, prion diseases, Nano-therapeutics, stem cell, nutritional biochemistry, acute phase reactants, metabolic and reproductive disorders and on many other current topics regarding veterinary biocemistry and clinical chemistry. The studies presented by the faculty members of Near East University attracted great attention.