Pharmacognosy

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Prof. Dr. İhsan ÇALIŞ
Prof. Dr. A. Hikmet MERİÇLİ
EFG 600
Master thesis study

EFG 601
The preparation and presentation of a topic related to natural products. This course introduces important points that should be considered in preparing a seminar presentation. For example, medical, beneficial and toxic drugs and auxiliary substances of natural origin, such as a plant or on one of the issues in the literature.

EFG 602
This course provides selection and application of chromatographic techniques in natural products research. Chromatographic techniques used for the purpose of detection, isolation and analysis in the pharmacognostical studies. The choice of optimum parameters for chromatographic methods and, how to make them the most suitable application in the analysis of natural compounds.

EFG 603
The objective of this course is to discuss main biosynthetic pathways of the primary and secondary metabolites in the plants, and the evaluation of the phytochemical studies of these metabolites.

EFG 604
To make the students able to learn the occurrence of iridoids and secoiridoids from terrestrial plants. To demonstrate their medicinal importance in phytomedicinal products in respect to their biological and pharmacological activities.

EFG 605
To make the students able to learn the occurrence of saponins (saponosides) from terrestrial plants and marine organism which are important in drug discovery studies and phytomedicine for their biological and pharmacological activities.

EFG 606
To make the students able to learn the occurrence of cardiac glycosides (cardenolides and bufadienolides) from terrestrial plants and animals for their biological and pharmacological activities.

EFG 607
The course aims to introduce a brief knowledge on the chemical structures of natural compounds and present the actual techniques used in their analysis in respect to their extraction, detection, isolation and structure elucidation. Further objective of the course is to show the richness of structural diversity in the nature and to give the methods used in isolation of the new bioactive compounds which can be used as the lead compounds in drug discovery studies. In this perspective, the diverse chemical structures isolated from terresterial plants and animals, microorganisms, insects and marine organisms will be introduced.

EFG 700
Doctorate thesis study

EFG 701
The aim of the course is to introduce primary metabolites from higher plants with respect to their general chemical characters (features), biological activities and the uses in the pharmaceutical industry.
In this perspective, the biosynthesis, chemical classifications, nomenclature, physical and chemical properties, methods for their production, detection, isolation and structure elucidation, distribution in nature, biological activities and the uses of of primary metabolites are introduced.

EFG 702
The aim of the course is to introduce phenylpropanoids (simple phenols, coumarins, lignans), xanthons, flavonoids, tannins, anthronoids and naphthalen derivatives which can be evaluated as potential active chemical constituents in drug discovery studies from the higher plants. Their biosynthesis, chemical classifications, nomenclature, physical and chemical properties, methods for their detection, isolation and structure elucidation, distribution in nature, biological activities and their uses are examplified.

EFG 703
The course aims to introduce the terpenoids (mono-, sesqui-, di-, and triterpenes, teriterpenic saponins, cucurbitacines, cyloartanes) from the natural sources having importance in the field of health and pharmaceutical industry together with their biosynthesis, classifications, nomenclature, physical and chemical properties, methods for their detection, isolation and structure elucidation, distribution in nature, biological activities.

EFG 704
The course aims to introduce the steroids (phytosterols, phytoecdysteroids, steroidal saponins, cardenolides and bufodienolides) from the natural sources having importance in the field of health and pharmaceutical industry including their biosynthesis, classifications, nomenclature, physical and chemical properties, methods for their detection, isolation and structure elucidation, distribution in nature, biological activities.

EFG 706
Objective of the course is to introduce spectroscopical methods used in the structure elucidation of the natural compounds. Mainly, introduction to NMR spectroscopy and basic principles will be discussed. The aim of the course is to to teach students structure elucidation by studying spectral features comparatively on the selected group in the natural compounds. Carbohydrates, glycosides and phenylpropanoids are the main subjects in the structure elucidation by UV, IR, NMR (1D- and 2D-NMR) and mass spectr.

EFG 707
Objective of the course is to introduce spectroscopical methods used in the structure elucidation of the natural compounds. Mainly, introduction to NMR spectroscopy and basic principles will be discussed. The aim of the course is to present structure elucidation by studying spectral features comparatively on the selected group in the natural compounds. Terpenoids (mono-, seski-, di- and triterpenoids) and steroids are the main subjects in the structure elucidation by UV, IR, NMR (1D- and 2D-NMR) and mass spectrometry.

EFG 708
The course aims to introduce the alkaloids under the perspective of their chemical structures, nomenclature, distribution in the nature and their biological activities which have a potential role in drug discovery studies.

EFG 709
The course aims to introduce the natural products used as anticancer agent together with their chemical structures, mechanisms of action, structure-activity relationships, dosage forms, and drugs in pharmaceutical market.

EFG 711