Pharmaceutical Chemistry

Also available in: Türkçe

Prof.Dr.Hakkı Erdoğan
Assist.Prof.Dr. Banu Keşanlı
Assist.Prof.Dr. Yusuf Mülazim
EFK 600
Master thesis study

EFK 601
The aim of this course is to give students basic knowledge on organic and pharmaceutical nomenclature principles according to IUPAC and Chemical Abstract rules. The students will learn how to draw the chemical structure from the name of a molecule as well as how to name a molecule from a given structure. General nomenclature principles and naming of some functional groups such as halogenated compounds, alcohols, ethers, phenols, aldehyde, ketone, amines, carboxylic acid and its derivatives, nitriles are presented.

EFK 602
This course provides general nomenclature principles, naming of functional groups, including hydrazine compounds, nitro and nitroso compounds, urea, carbamate, sulfur containing compounds, rings and bicyclic systems, and heterocyclic compounds.

EFK 603
Investigation of basic reaction types and mechanisms in organic chemistry including the below give topics are discussed: Fundamentals of structure and reactivity. Carbon-carbon covalent bonding, carbon-oxygen and carbon-nitrogen bonding and structure types. Electronegativity, cyclic hydrocarbons and isomerization. Atomic and molecular orbitals, bonding and hybridization. Terms and terminologies: acids, bases, electrophiles, nucleophiles, hard and soft acid concept as applied to organic molecules. Classification and determination of reaction mechanisms. Understand the various methods which are used in elucidating reaction mechanisms

EFK 604
The aim of this course is to provide detailed exposure to some of the key areas of organic chemistry including a detailed appreciation of nucleophilic substitution, intramolecular reactions, basic carbonyl chemistry and electrophilic aromatic substitution with reference to case studies in organic synthesis of complex products.

EFK 605
This course provides students with a background in modern analysis with an emphasis on instrumentation. Fundamental theoretical principles, capabilities, applications, and limitations of modern analytical instrumentation used for qualitative and quantitative analysis are provided through specific examples and extensive problem solving. The instruments studied include UV-Vis, FTIR, NMR, Mass Spectroscopy.

EFK 606
Quantitative and qualitative identification of organic compounds principally by using mass, vibrational, nuclear magnetic resonance, and chromatographic methods is provided. Structure spectra correlations applied to organic compounds with examples drawn from diverse areas of medicinal chemistry are discussed.

EFK 607
Preparation and presentation of a recent topic in pharmaceutical chemistry

EFK 608
The course aims to acquaint students with understanding of organic chemistry and application of its principles in analyzing pharmaceuticals. Advance organic chemistry course is designed to provide thorough knowledge of the fundamental aspects of organic chemistry, reaction mechanisms and functional group chemistry, particularly relating structure to properties; some spectroscopic techniques applicable to a wide range of chemical studies.

EFK 609
The course objective is to teach basic laboratory safety rules and guidelines together with how to work with various chemicals. Safe laboratory techniques, storage of chemicals, compatibility of series of chemicals typically used in a lab setting are explained.

EFK 610
The course objective is to teach microwave assisted organic reaction method and recent developments in this field. Use of microwave reactor in organic synthesis and application of this method to various organic reactions is provided.

EFK 611
To educate and instruct students with basic knowledge in organic chemistry especially with functional groups of organic compounds; their general structures, properties, synthesis and reactivities.

EFK 612
To educate and instruct students with basic knowledge in literature research and reading. Developed by: reading, discussing and writing about short narrative texts.

EFK 614
The course objective is to educate and instruct students with the principles of development and design of new drugs; importance of physiochemical properties, drug-receptor interactions, chemical structure, structure activity relationship in drug design will be discussed.

EFK 700
Doctorate thesis study

EFK 701
This course is designed to recognize and utilize the major reaction mechanisms, especially those involving intermediates: Electrophilic addition, elimination, oxidation-reduction, electrophilic aromatic substitution free radical. Understanding of organic reaction mechanisms involving radical reactions and application of radical reaction mechanisms in drug synthesis is discussed by exploring specific examples that is relevant to medicinal chemistry.

EFK 702
To extend knowledge of important reaction mechanisms, building upon Organic Reaction Mechanism I, II and III courses. Strategies in organic synthesis, reactivity, molecular rearrangements, reaction intermediates, enzymatic reactions, stereoelectronic effects are elucidated.

EFK 703
Application of Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) techniques in determination of structure of organic compounds, pharmaceuticals is presented. This course is based on solving various examples of both simple and complex chemical structures by using these instrumental methods.

EFK 704
This course presents fundamentals of drug synthesis in industrial settings, types of instruments, equipment used as well as various methods utilized. This course provides understanding of development and optimization of synthesis methods and how that applies to scale-up processes and operations