Molecular Medicine

Also available in: Türkçe

  • Professor Gamze Mocan, MD
  • Professor Nerin Bahçeciler Önder, MD
  • Associate Professor Bahar Kaymakamzade Çulhaoğlu, MD
  • Associate Professor Pınar Tulay, PhD
  • Associate Professor Rasime Kalkan, PhD
  • Assistant Professor Hanife Özkayalar, MD
  • Assistant Professor Mahmut Çerkez Ergören, PhD
  • Assistant Professor Kerem Teralı, PhD
  • Assistant Professor Umut Fahrioğlu, PhD
  • Ferdiye Taner, PhD
COURSE CODE COURSE NAME T U K
MM601 Current Topics in Cell and Molecular Medicine 3 0 3
MM602 Molecular Techniques in Medicine 2 4 4
MM603 Molecular Cell Biology 3 0 3
MM604 Molecular Genetics 3 0 3
MM605 Medical Biochemitry 3 0 3
MM606 Molecular Microbiology 3 3 4
MM607 Molecular Pathology 3 3 4
MM608 Cell Culture 0 4 4
MM609 Stem Cell Biology 3 0 3
MM610 Molecular Developmental Genetics 3 0 3
MM611 Bioistatistics 3 0 3
MM612 Molecular Embriology and Histology 3 0 3
MM613 Reproductive Medicine 3 0 3
MM614 Introduction to Immunology 3 0 3
MM615 Virology 3 0 3
MM616 Bioethics 2 0 2
MM617 Experimental Animal 2 4 4
MM618 Literature Evaluation and Publication of the Scientific Research 2 0 2
MM619 Seminar 0 0 0
MM620 Thesis Studies 0 0 0

MM 601
This course will build from the basic genetic concepts of molecular genetics. Some of the topics addressed include autism spectrum disorders, direct to consumer testing, pain management, complex genetic mechanisms, chronic conditions, screening programs, pharmacogenetics, and emerging genetics specialities.

MM 602
A comprehensive study of molecular biology applications and techniques as they relate to medicine. The topics covered in this course include mRNA isolation and Northern blotting, gene cloning, mutation of DNA, real-time quantitative PCR, bioinformatics, expression of recombinant proteins.

MM 603
The course is designed to provide students with a firm grounding in molecular biology, on which they can integrate more complex concepts addressed in upper level course offerings.

MM 604
This course will provide information regarding etiology, features, testing, and treatment for a variety of genetic conditions.

MM 605
Medical biochemistry addresses the functioning of normal and diseased organisms from a biochemical point of view.

MM 606
Basic concepts of microbial genetics; bacterial genomes and basic functions; Microbial replication, transcription and translation; microbial gene organization and Operon; Plasmid; Transduction; Transposition; Transformation; Conjugation; DNA Mutation and DNA Repair; Viral Genetics will be thought.

MM 607
This course aims to provide you with a wide and detailed understanding of the various aspects of molecular pathology.

MM 608
This course provides graduate-level knowledge of and expertise in animal and plant tissue culture theory and practice.

MM 609
Students will learn about The different types of stem cells, how they are derived and the extent of their plasticity; How tumor stem cells give rise to metastases and treatment-resistant remnant cells that cause relapse, and how this impacts on the development of future cancer treatment strategies; How epigenetic mechanisms encompassing various DNA modifications and histone dynamics are involved in regulating the potentiality and differentiation of stem cells; How microRNAs are involved in regulating stem cell differentiation;How stem cells are currently being used in the clinic and what kinds of future treatments lie on the horizon. Students will also be exposed to current Norwegian projects lying at the frontier of stem cell research

MM 610
This course covers the current understanding of the molecular mechanisms that regulate human development. Specific topics include formation of early body plan, cell type determination, organogenesis, morphogenesis, stem cells, cloning, and issues in human development.

MM 611
An introduction to descriptive statistics, measures of central tendency and variability, probability distributions, sampling, estimation, confidence intervals and hypothesis testing. Computing is introduced and used throughout the course.

MM 612
From the observation of macroscopic morphology of the human body structure, combined with observation of the microscopic structure of a variety of human cells, tissues, organs, etc., through the microscope, build the cognitive concepts for cells, tissues, and organs composing the human body system and structure and further combine structure with function.

MM 613
The course provides training in reproductive and developmental medicine for scientists, clinicians and others, for instance ethical advisers or lawyers looking to specialise.

MM 614
A detailed introduction to the basic principles of immunology and a clinically-oriented lecture series will be given to students.

MM 615
The basic thesis of the course is that all viruses adopt a common strategy. The strategy is simple. Viral genomes are contained in metastable particles. Genomes encode gene products that promote an infectious cycle (mechanisms for genomes to enter cells, replicate, and exit in particles). Infection patterns range from benign to lethal; infections can overcome or co-exist with host defenses.

MM 616
Ethical issues in designing, conducting, analyzing and presenting research; includes historical and theoretical background as well as case studies.

MM 617
Introduction to the relevant legal framework, pain physiology, anaesthesia, opinions on animal testing, alternatives to animal testing, stabling of experimental animals, standardisation of procedures, handling of animals, genetic aspects of the selection of animals, form filling, consequences of prohibition of animal testing, demonstrations and practice in the use of experimental animals.

MM 618
Students will prepare a literature review on the subject of their chosen research project in order to formulate research questions, and allow them to formulate a research outline. They will be expected to critically evaluate published primary research articles, and develop skills in clear and accurate scientific communication.

MM 619
Students should be attended all the scientific seminarts organized by Near East University Institute of Health Sceinces and Experimental Health Sciences Centre (DESAM).

MM 620
Writing a publishable research project thesis during master education.

COURSE CODE COURSE NAME T U K
MM701 Proteomics and Metabolomics 3 0 3
MM702 Molecular Mechanism Approaches in Diagnosis 2 4 4
MM703 Medical Genetics 3 0 3
MM704 Bioinformatics 4 0 4
MM705 Immunogenetics 3 0 3
MM706 Research Ethics 3 0 3
MM707 Nutrigenetics/ Nutrigenomics 3 0 0
MM708 Pharmacogenetics/Pharmacogenomics 3 0 3
MM709 Prokaryotic and Microbial Genetics 2 4 4
MM710 Population Genetics and Genetic Epidemiology 3 0 3
MM711 Prenatal Genetics Diagnosis and Fetal Medicine 3 0 3
MM712 Human Malformations in Molecular Medicine 3 0 3
MM713 Genetic Counciling 3 0 3
MM714 Advanced Stem Cell Techniques 2 4 4
MM715 Cardiogenetics and Vascular Biology 3 0 3
MM716 Genome Editing 3 0 3
MM717 Neuroscience and Neurodegenerative Disorders 3 0 3
MM718 Literature Evaluation and Publication of the Scientific Research 2 0 2
MM719 Intellectual Developmental Seminars 0 0 0
MM720 Thesis Studies 0 0 0

MM 701
Omics’ technologies allow the components of a living organism to be appreciated in their entirety by providing insight into gene expression, protein synthesis and function and metabolic networking. This course builds upon concepts by covering the basic principles of proteomics and metabolomics and their application in the new systems biology ‘omics’ approach to scientific discovery. This course will emphasize both the methodologies used in proteomics and metabolomics, as well as their applications in both research and medical diagnostic settings.

MM 702
This course is about understanding molecular mechanisms of disease and using this understanding in disease prevention, diagnosis and treatment.

MM 703
The course will give an overview of mechanisms for development of genetic diseases. Topics include different patterns of inheritance, like dominant, recessive, autosomal and sex linked inheritance.

MM 704
The course introduces students to biological problems and systems that benefit from interrogation through bioinformatics and computational biology.

MM 705
The genetic basis of self/non-self discrimination underlies all immune responses and can influence disease susceptibility at the level of both individual and populations.

MM 706
Students wıll be able to recognise and analyse key research ethical questions, to formulate ethical research plans and responses to ethical challenges by applying key ethical theories and approaches, to recognise and understand key ethical principles guiding research and how they apply to research work, to identify rights and responsibilities as a researcher and to understand how ethical decisions and choices influence society and research community.

MM 707
This course focuses on nutrigenomics, the effect of diet on gene expression, and nutrigenetics, how genetic differences affect nutrient uptake and metabolism.

MM 708
Pharmacogenomics is the study of how the genome affects the body’s response to drugs. This branch of science holds the promise that drugs might be tailored for individuals and adapted to a patient�s personal makeup, thus improving efficacy and safety. Pharmacogenomics combines traditional pharmaceutical sciences such as biochemistry with specific knowledge of genes, proteins, and single nucleotide polymorphisms.

MM 709
Basic concepts of microbial genetics; bacterial genomes and basic functions; Microbial replication, transcription and translation; microbial gene organization and Operon; Plasmid; Transduction; Transposition; Transformation; Conjugation; DNA Mutation and DNA Repair; Viral Genetics will be thought.

MM 710
This course is designed to familiarize you with the field of population genetics, the branch of evolutionary biology concerned with the genetic structure of populations and how it changes through time. Population genetics is the backbone of evolutionary biology because changes in the genetic composition of a population are the basis for the most of other evolutionary changes.

MM 711
This course will review human embryology, the teratogenic factors leading to abnormal development, and the common indications for prenatal genetic counseling, including advanced maternal age, abnormal serum screening, ultrasound anomalies, diagnostic procedures, and prenatal complications

MM 712
This course will introduce students to the basic concepts and principles of human genetics and their clinical applications. Topics include the chromosomal, molecular, and biochemical basis of disease, prenatal diagnosis, genetic counseling, bioinformatics, and congenital anomalies.

MM 713
This course will provide an overview of diagnoses, demonstrates techniques for building a helping relationship, and treatment approaches for a wide range of disorders including depression, trauma, anxiety disorders, and problems of living.

MM 714
The aim of the course is to bring together cell biological, biochemical, anatomic, histological, physiological and evolutionary medical views to a coherent picture of stem cells in an experimental and clinical context.

MM 715
This unit aims to introduce the students to basic terminology and principles in cell biology relevant to vascular biology, to demonstrate how molecular mechanisms in cell biology contribute to the pathology of vascular diseases, to introduce students to the basis of risk factors and genetic susceptibility to cardiovascular disease, to train students to apply these molecular techniques in an appropriate situation to gain further knowledge about vascular biology, to provide basic data analysis skills which students should apply throughout the rest of the Cardiovascular Pathway and specifically during their research project

MM 716
This theoretical course will provide an overview of the principles and use of the CRISPR/Cas9 system for genome editing/engineering.
Ders Kitabı ve Yardımcı Kitaplar: Targeted Genome Editing Using Site-Specific Nucleases ZFNs, TALENs, and the CRISPR/Cas9 System Editors: Yamamoto, Takashi (Ed.)

MM 717
Students will prepare a literature review on the subject of their chosen research project in order to formulate research questions, and allow them to formulate a research outline. They will be expected to critically evaluate published primary research articles, and develop skills in clear and accurate scientific communication.

MM 718
Students should be attended all the scientific seminarts organized by Near East University Institute of Health Sceinces and Experimental Health Sciences Centre (DESAM).

MM 719
Writing a publishable research project thesis during PhD education.